Friends and Allies
- “Turns out, I don't need a medal to tell me I'm a good guy. Because if that little kid likes me, how bad can I be?”
- ―Ralph, about Vanellope (last line in the film)
Vanellope also changed Ralph for the better as she helped him understand what it really means to be a hero, as he decided to sacrifice himself to save her when King Candy and the Cy-Bugs took over Sugar Rush. Their relationship became similar to that of a big brother and little sister and grew into a very heartwarming one at that. Vanellope even offered Ralph a room in her castle after she turned out to be the rightful ruler of Sugar Rush, though he humbly denied as their friendship alone was enough to keep him happy.
Vanellope did not have much interaction with Fix-It Felix, Jr., the eponymous hero of his game; however, Felix protected Vanellope from the oncoming hoard of Cy-Bugs during the climax.
King Candy was Vanellope's mortal enemy. When taking over Sugar Rush, King Candy hijacked into the codes of the game and tried to delete Vanellope's code, turning her into a glitch. He also locked up the character's memories, making them turn on Vanellope as well and regard him as the rightful ruler. King Candy was determined not to let Vanellope race at all, as if she was to cross the finish line in an official race, the game's codes would be restored.
Out of all the Sugar Rush Racers, Taffyta had the most significant animosity towards Vanellope, believing that she was a glitch and not supposed to participate in races. She led the other racers in destroying Vanellope's kart, the "Likkity-Split," and later ordered Candlehead to rid Vanellope during the Random Roster Race. However, after Sugar Rush was restored, the racers and citizens regained their memories, and Vanellope is revealed to be the rightful ruler of Sugar Rush (a princess), Taffyta did not hesitate to apologize for her behavior towards the young princess and reconciled with her.