Experiment 275 was the 275th genetic experiment created by Jumba with Hämsterviel's funding. She was designed to tickle people into hysterics. 275 and the other first 624 experiments were deactivated and smuggled to Earth by Jumba during his mission to capture Experiment 626.
All the experiments were released and scattered across the island of Kauai.
At an unknown point after this, Experiment 275 was activated and captured by Gantu.
In "Snafu", Tickle-Tummy was freed along with Gantu's other captive experiments by Lilo, Stitch, and several other experiments in a rescue mission. She then tickled Reuben into hysterics, after he denied being ticklish.
The first 624 experiments, including Tickle-Tummy, were rounded up by Leroy and taken to a stadium to be destroyed. However, Lilo, Stitch, Jumba, Pleakley, Reuben and Gantu arrived before the experiments could be destroyed.
It is unknown whether or not Tickle-Tummy participated in the following battle between the experiments and the Leroy clones.
The Leroys soon gained the upper hand in the battle, but were defeated when Lilo, Stitch, Reuben and several other experiments performed the song "Aloha `Oe," which caused the Leroy army to shut down due to the original Leroy's fail-safe.
Tickle-Tummy made an appearance in the Stitch! anime along with Frenchfry, Squeak, Pix, and Houdini after Hämsterviel kicked them out for being considered useless. She makes another appearance in the anime with Squeak, Clip, Nosox, and Retro.
- Tickle-Tummy was not on the list of the original 626 experiments in the end credits of Leroy & Stitch, but she is actually 275, a number taken by Wormhole in Stitch!. The creators decided to put Wormhole's name in place of Mamf (the one who used to be 272). So Wormhole is now 272.
- Tickle-Tummy's pod color is white.