Doctor Octopus contacted the Frightful Four to kidnap Spider-Man. With the help of Trapster, Thundra and the Frightful Four (sans Trapster) tracked Spider-Man to Midtown High School. She got distracted by Peter, who changed to his spider costume. She fought with Spider-Man for a while and escaped before the police arrived.
After Spider-Man left S.H.I.E.L.D., the Frightful Four (sans Trapster) ambushed Spider-Man for a rematch. They got the tide of the battle until Spider-Man's previously rejected teammates arrived and saved him, Thundra fought with Power Man, but eventually got trapped in Spider-Man's web.