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The Annihilator is a main villain in the series, Mighty Med and the nemesis of Skylar Storm and Hapax the Elder former apprentice, as well as the archenemy of Kaz and Oliver. He was the villain who caused Skylar to lose her powers and turn her evil. He serves as one of the two main antagonists in Season 2, replacing Wallace and Clyde. After his death, Mr. Terror became the second main antagonist in the second season. The Annihilator main power is Power Absorption and has a similar mutation like his mentor Hapax the Elder.

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