In her later years, Ganzel has had several voice-over roles on cartoons, animated movies, and series, including Cow and Chicken, The Emperor's New School, Monsters, Inc., Goof Troop, Aaahh!!! Real Monsters, Rugrats, and Horton Hears a Who!. Her first venture into voice acting was playing Kitty Glitter in Top Cat and the Beverly Hills Cats. Most likely, her most well-known role in animation is Miss Vavoom. The character is an homage to all of the sexy film stars, singers, and damsels in distress, who served as Droopy's love interest in the Tex Avery cartoons. She appears in Tom and Jerry Kids and Droopy, Master Detective.
Ganzel was also a panelist in the Bauman and Davidson Versions of Hollywood Squares.
- Darkwing Duck (1991): Flygirl/Preena Lot
- Goof Troop (1992): Duke's girlfriend
- Monsters, Inc. (2001): Additional voices
- The Emperor's New School (2006): Princess Lalala
- Cars (2006): Additional voices
- WALL-E (2008): PR-T (the Beautician Bot)
- Up (2009): Additional voices
- Toy Story 3 (2010): Additional voices
- Monsters University (2013): Additional voices