- 1982 - Day One of the formal grand opening of Epcot begins.
- 1997 - Walt Disney World announces their plans to close Mr. Toad's Wild Ride.
- 1961 - The Walt Disney's Wonderful World of Color episode "The Hunting Instinct" premieres on NBC.
- 1987 - The DuckTales episode "Earth Quack" premieres in syndication.
- 1990 - The TaleSpin episode "Whistlestop Jackson, Legend" premieres in syndication.
- 1992 - The Goof Troop episode "All the Goof That's Fit to Print" premieres in syndication.
- 1993 - The Bill Nye the Science Guy episode "Digestion" premieres in syndication.
- 1994 - The Little Mermaid episode "The Beast Within", the Aladdin episode "The Spice is Right" premiere on CBS, and the Bill Nye the Science Guy episode "The Sun" premieres in syndication.
- 1996 - The Quack Pack episode "Snow Place to Hide" premieres in syndication.
- 1997 - The Bear in the Big Blue House episode "Mouse Party" premieres on Playhouse Disney.
- 2000 - The Buzz Lightyear of Star Command episode "Stress Test" premieres on UPN and in syndication.
- 2002 - The Rolie Polie Olie episode "Making the Best of It/Superest Bot of Them All/Oh Olie, Olie it's a Wired World" premieres on Playhouse Disney.
- 2004 - The Kim Possible episode "Bonding" premieres on Disney Channel.
- 2005 - The American Dragon: Jake Long episode "The Halloween Bash" and The Buzz on Maggie episode "The Big Score/Scare Wars" premiere on Disney Channel.
- 2007 - The Emperor's New School premiere on the Disney Channel with the episode "Curse of the Moon Beast/Aww, Nuts!".
- 2010 - The Suite Life on Deck episode "Senior Ditch Day" and the Fish Hooks episode "Doggonit" premiere on Disney Channel.
- 2012 - The Kickin' It episode "Sole Brothers", the Lab Rats episode "Mission Invisible", the Pair of Kings episode "Inconvenient Tooth", and the Crash & Bernstein episode "Coach Crash" premiere on Disney XD.
- 1990 - Fantasia
- 1897 - Ettore Boiardi (chef and founder of Chef Boyardee)
- 1938 - Christopher Lloyd (actor)
- 1942 - Annette Funicello (actress and singer)
- 1946 - Richard McGonagle (actor and voice actor)
- 1950 - Patricia Parris (voice actress and actress)
- 1952 - Jeff Goldblum (actor)
- 1954 - Ellen Gerstell (voice actress)
- 1972 - Saffron Burrows (actress)
- 1986 - Kyle Gallner (actor)
- 1964 - Gage Clarke (actor)
- 1995 - Mary Wickes (actress)
- 2006 - Arthur Hill (actor)
- 2012 - Russell Means (activist, politician, musician, and actor)
|<<||October 21||Timeline||October 23||>>|