Due to his disarming cuteness, Mr. Stenchy gains very much attention from humans and even certain alien species, but not so much from other experiments. He also appears to act as cute as he looks, being very loving and friendly towards anyone who gives him affection.
Experiment 254 was the 254th genetic experiment created by Jumba with Hämsterviel's funding. He was designed to use his cuteness to smitten Jumba's enemies into taking him back to their headquarters, where 254 would emit a noxious odor that would make 40 square miles of the area uninhabitable for decades. 254 and the other first 624 experiments were deactivated and smuggled to Earth by Jumba during his mission to capture Experiment 626.
All of the experiment pods were released and scattered across the island of Kauai.
At an unknown point after this, Experiment 254 was activated.
Lilo fell for 254's cuteness and decided to keep the newly-christened Mr. Stenchy, despite Jumba's warnings of the experiment's inevitable stench that he'd eventually unleash. Stitch, however, became jealous of Mr. Stenchy and was immune to the latter's charm. He even relentlessly bullied and tormented Mr. Stenchy.
Later, Lilo began taking Mr. Stenchy to Mertle's tea parties in an attempt for the former to be accepted into their group. Of course, Mertle and the hula girls had fallen for Mr. Stenchy's charm after Lilo first introduced him to them.
When Stitch was left home alone with Mr. Stenchy, the latter made a vain attempt to befriend Stitch, not wanting them to be enemies. However, Stitch ignored Mr. Stenchy's efforts and ended up locking the pint-sized experiment in the pantry. Gantu later attacked the house, but Stitch (having two shoulder devils) goaded Gantu into taking Mr. Stenchy so that the former would be rid of them both.
However, back at his ship, Gantu also fell for Mr. Stenchy's charm before he could teleport the latter to Hämsterviel. This made Experiment 625 envious like Stitch, though Gantu took little notice and kept pampering Mr. Stenchy.
Thus, Gantu grew closely attached to Mr. Stenchy until Lilo, Stitch, Jumba and Pleakley broke into the ship to save Stitch's cousin. Due to Stitch abandoning him, Mr. Stenchy chose Gantu. However, Mr. Stenchy then began to emit his stink, forcing Gantu to hand the former over. Although Mr. Stenchy reeked, it didn't faze Pleakley at all.
After being rescued, Mr. Stenchy was sent to Plorgonar in a rocket, where he could be loved in spite of his malodorous smell, as it was considered appealing on Pleakley's home planet.
Mr. Stenchy inexplicably reappeared back on Earth and not producing his deadly stink, suggesting it wears off after a while.
Later, the first 624 experiments, including Mr. Stenchy, were rounded up by Leroy and taken to a stadium to be destroyed. However, Lilo, Stitch, Jumba, Pleakley, Reuben and Gantu arrived before the experiments could be destroyed.
Mr. Stenchy participated in the following battle between the experiments and the Leroy clones, as in one scene, Mr. Stenchy can be seen around some of the Leroys just before they started to shut down.
The Leroys soon gained the upper hand in the battle, but were defeated when Lilo, Stitch, Reuben and several other experiments performed the song "Aloha ʻOe", which caused the Leroy army to shut down due to the original Leroy's fail-safe.
Mr. Stenchy appeared twice in the Stitch! anime. He was first seen when he fell in love with Stank, and again later on when Hämsterviel made numerous clones of him and Mrs. Sickly as Christmas toys. It is revealed that when his stench is combined with Mrs. Sickly's, it could cause an explosion that has the power to destroy a planet.
- Mr. Stenchy was first revealed in a DVD bonus feature of Stitch! The Movie in the experiment gallery.
- Mr. Stenchy is one of the rare experiments to have sclerae and pupils instead of solid black eyes, the others being Mrs. Sickly, Skip, Clink and Nosox.
- Stitch and Reuben were unmoved by Mr. Stenchy's cuteness, as Jumba pointed out that other experiments are immune to Mr. Stenchy's charm.
- Pleakley is revealed to be the only one able to tolerate Mr. Stenchy's stink, unlike everyone else.
- Mr. Stenchy's pod color is green.
- Mr. Stenchy is described by the experiment computer screen as, "Experiment 254. Primary function: Stink bomb. Emits a noxious odor that makes the location inhospitable."
- Mr. Stenchy is one of the only experiments whose one true place is not on Earth.
- In Leroy & Stitch, Mr. Stenchy inexplicably returned to Earth from Plorgonar. Also, he did not produce his stink, suggesting it wears off after a while or he has learned how to control it.
- Mr. Stenchy is one of the few experiments to not appear in the group photo at the end of Leroy & Stitch.
- In the Stitch! anime, Mr. Stenchy has a wife named Mrs. Sickly.
- Mr. Stenchy's head, antennae and ears appear in the online game Jumba's Lab.