She also voiced Nita in the 2006 direct-to-video Disney film Brother Bear 2, Mara in the Disney XD animated series Tron: Uprising, Sheriff Callie in the Disney Junior series Sheriff Callie's Wild West, and played Lana Thomas, the high school rival to Anne Hathaway's Mia Thermopolis, in the 2001 hit Disney comedy film The Princess Diaries.
Some audiences have noted certain similarities between Moore, and her character Rapunzel, such as their facial features and personality. Also, Moore is famous for frequently changing her hairstyle and color from short and brown, to long and blonde, or vice versa, similar to Rapunzel. Furthermore, Rapunzel is seen barefoot throughout the majority of the film. Likewise, it is a known fact that Mandy Moore as a singer, enjoys performing barefoot. She also played Mary Portman in 4 episodes of Grey's Anatomy and Dr. Erin Grace in the ABC Studios show Red Band Society.