- “You'll see me again as a CONQUEROR!”
- ―Mad Doctor[src]
Dr. XXX, better known as "The Mad Doctor," is the main villain of the 1933 Mickey Mouse short of the same name. He wants to attach Pluto's head to the body of a chicken in order to "find out if the end result will bark or crow or cackle."
As his name suggests, the Mad Doctor is very murderously insane and takes much joy in causing harm to others, but makes up for it at being a scientific genius. His work always consists of dark cutting machinery and various other contraptions, most of which are used in his deadly experiments; though some of his gadgets have served a purpose, as the Beetleworx were at one point a construction crew. In Epic Mickey, his personality is expanded; though insane, he is also very conniving and manipulative as he uses the jealousy of Oswald to distract Mickey while he works closely with the Shadow Blot (whom he is also using for his own purposes). It is even shown that when he is working for Oswald in Epic Mickey: Tales from the Wasteland that while seemingly trying to help the rabbit, he is in reality waiting for the right time to double-cross him and take control of Wasteland.
In the original cartoon, Mickey hears Pluto yelping for help in the middle of a stormy night. He looks out the window to find that Pluto is being kidnapped by a man in a black cloak. Mickey follows them to a castle. Unfortunately, Mickey loses them and travels through the mysterious castle to save Pluto. While Mickey is searching, the man in the cloak reveals himself to be a mad scientist to Pluto. He also shows his plan to attach Pluto's head to the body of a chicken to see if it will bark, crow, or cackle, through the song The Great Experiment. Soon enough, Mickey arrives but is strapped down and captured. The Mad Doctor decides to eliminate Mickey by experimenting on him. Just when Mickey is about to meet his demise, he awakens in his bedroom. It turns out, that it was all a nightmare.
Even though the cartoon says he doesn't exist, he became a comics character, although never a recurring one. He appears in the Italian story Topolino e i casi "X" "Y" "Z", as an hypnotizer who try to make of Eega Beeva his slave to rob him the plans of a top-secret neutronic motor. He also appears in various illustrations.
The Mad Doctor appears as a boss in the video game Mickey Mania. He appears in the second level, named after his self-titled episode, where he has held Pluto captive. He will throw a potion at Mickey as a means of attack. Any attack method will work on him (jumping, throwing marbles), however, he will toss around many potions after attacking him. Once he is defeated, Pluto is rescued.
Epic Mickey seris
Years ago, when the Mad Doctor arrived in Wasteland, his immediate priority was to seek power. Becoming a close partner to Oswald, he constructed the Beetleworx as a construction crew to help improve the land as new arrivals came in. But when Mickey created the Shadow Blot and the Blot Wars began, he quickly switched sides and became the Blot's closest ally. He offers the Blot the opportunity to become a beloved cartoon star in his own right (the desire of all cartoon characters) and sets his plot into motion to drag Mickey back into Wasteland and set him and Oswald against each other. He is later shown to be an animatronic (this is so when the Blot sucks the paint out of Wasteland), only the animatronics would survive, and he would be their ruler. After a battle with Mickey, the Doctor is shot up into the sky on his machine and isn't seen for the rest of the game.
- “The Mad Doctor is making his return from banishment in Disney Epic Mickey 2 as a reformed Toon. Seeing the error of his ways he offers his help, but the question is, can Mickey, Oswald, and Gus trust their old nemesis? What do you think?”
- ―Epic Mickey Facebook description
In the sequel, the Mad Doctor has shown his face again in Wasteland, claiming he had a change of heart and is now ready to help the other Toons rebuild Wasteland after the recent strings of earthquakes. After making his grand re-entrance in Mean Street, he manages to gain Oswald's ear again and begins telling him of how he plans to help repair Wasteland and warning him of the Blotworx, creatures born of a Spatter fused with the mechanical parts of a Beetleworx. However, not believing the Mad Doctor's story, Gus and Ortensia successfully reach out to and call Mickey back to Wasteland to help with the Mad Doctor.
Throughout the game, the Mad Doctor speaks mostly in song and has been singing about how he wishes to change back from animatronic to Toon (he did so because he wished to control the Blot). He is in a race against time as his animatronic parts are beginning to break down. After Mickey and friends defeat the grumpy and stubborn gremlin Prescott, the Mad Doctor and one of his Beetleworx appears with Animatronic Daisy, her Blotling cameraman and Pete, surprising the group before his Beetleworx hypnotizes Prescott into taking the fall for everything that had happened. After, he announces his plans to build a new attraction in Wasteland to lift everyone's spirits after everything that has happened.
However, as Mickey and Oswald discover later, his good acts were all a ploy for his true motives: to become a Toon again and leave Wasteland to destruction. While traversing through the World of Evil projector, the doctor reveals (in song) that he survived his last battle and crash landed in the Disney Gulch, beginning to scheme of his revenge against Wasteland. He created the Blotworx to be his new army, but had to outcast them because of their unpredictable nature. They discover more of the doctor's plans after discovering his old attic from Lonesome Manor. While he caused Prescott to turn on his friends, he had him build a television (similar to the one Gus uses to call Mickey) to broadcast his show to the cartoon world. While he also used guardian siphons to pull the guardians out of Wasteland, the REAL reason for Wasteland's recent earthquakes, he would use them to become a Toon again and he would be able to leave Wasteland after the cartoon world remembered him enough so he could escape.
Mickey and Oswald used a projector in the Mad Doctor's Attic to go back to Mean Street in time where the doctor's scheme was already in motion and he used his new attraction to trap Ortensia, Clarabelle, and Horace. He then gave the heroes an ultimatum: give him the brush so he could become the most powerful villain in the cartoon world or watch as he would destroy Wasteland and thin out their friends. With help from Oswald, the heroes chose to fight and successfully defeated the doctor. There are two endings to the battle (something unlike that happened with the Blot).
In the Thinner ending, Mickey frees Oswald from the Mad Doctor's clutches when he tried to save him and they are blasted back to the surface of Mean Street as he falls into the thinner below. In the Paint ending, after Mickey sprayed paint in his face to save Oswald, the doctor has a change of heart and uses rocket shoes to propel himself and them back towards Mean Street. After Ortensia, Clarabelle, and Horace are free, he then asks how they could have the heart to save him after all he did, to which Mickey and Oswald tell him that's what "heroes" do, the same reason he saved them. Hearing this, he then understands what true respect comes from (not from power, but from courage and love) as the guardians react to this and convert him back to a Toon. He then thanks Mickey and Oswald and exclaims that he will truly be good again. He is last seen as a truly reformed Toon on a parade float with Mickey, Oswald, Ortensia, and Gus in the end.
- Master Xehanort, the primary antagonist from the Kingdom Hearts series is heavily reminiscent of the Mad Doctor.
- In the Roger Rabbit cartoon short, Tummy Trouble, the Mad Doctor's photo can be seen in the doctor's office and the Toontown hospital.
- In the direct-to-video Aladdin and the King of Thieves, one of the forty thieves, clearly identifiable as a fakir, is similar to the Mad Doctor.
- Ecks, Doublex, and Triplex, a trio of evil scientist anthropomorphic monkeys appearing in Mickey Mouse comic books and comic strips, are inspired by the Mad Doctor. The name of the third of them, Triplex, is a a reference to the real name of the Mad Doctor (Dr. XXX, which can be read "Dr. Ex-Ex-Ex" or… "Dr. Triple X").