Mabel is an old woman who lives on the outskirts of Paris in a quaint village. Remy, along with the rat colony, lives there in her attic. Mabel loves to cook, proven by her collection of many different foods, and is always seen watching Gusteau on the television. She also owns Gusteau's famous cookbook: "Anyone Can Cook", which is always left in the kitchen, causing Remy to visit her kitchen regularly. Later, when Mabel sees Remy in her kitchen, she grabs a shotgun and shoots at him while accidentally blowing numerous holes in the ceiling, causing it to crash to the floor, with hundreds of rats falling with it. The rats begin to flee from her home, but Mabel still doesn't leave her infestation to that. She puts on a gas mask and starts spraying a gaseous rat poison at the rats. Remy was her main target because he was the last to escape. She soon gives up after the rats escape in their "rescue boats," and after missing her final shot at Remy, who was floating on her stolen cookbook. She isn't seen for the remainder of the film.
Mable is an avid fan of Gusteau, as she often watches him on the telly. She also loves cooking, given her large collection of herbs and spices. In addition, she has a fear of rats, and has a trigger-happy personality rooted in her youth, when she participated in the French Resistance against the Nazi occupation in World War II (shown in pictures which can be seen in her house). Age and a lack of any recent practice have numbed her aim, as she wrecks her house far more than the rats ever could, shooting at them and accidentally destroying the ceiling of her house in the process. She also possesses a gas mask and rat spray, which she could have used in the first place instead of her gun.
- Her gun is similar to the one of Charles Muntz's from Up.
- She is set to be the main antagonist in the upcoming Sequel.