Eddie pursues Jessica into Toontown believing she just committed murder. He then notices a woman resembling Jessica in a hotel window and proceeds to intercept. Once there, the stunning woman immediately reveals herself to be an ugly hag named Lena Hyena. Thinking Eddie came to visit her out of romantic intent, Lena becomes instantly smitten and chases after him in a lustful, chaotic spasm. Not knowing where to turn, Eddie quickly retreats into a men's restroom.
Eddie discovers the restroom is non-existent leading to open air miles high in the sky and plummets countless stories. Just as he's about to hit the street below, Lena catches him and gives him a big kiss him very much to his dismay. Still madly passionate for Eddie, she continues after him. Eddie then quickly tears a street line and places it towards a brick wall to which Lena mindlessly follows, flattening upon impact.
Roger Rabbit's Toontown
Lena appears in the Roger Rabbit's Toontown issue, "The Kissing Bandit" where it's revealed she's actually been a long-time friend of Jessica. In the issue, Jessica visits Lena in Toontown as she's pursued by a Toon Wolf who's overly smitten by her. The Wolf keeps confusing Lena for Jessica in his multiple attempts to kiss her, much to his horror. He runs away not knowing what to learn from his shenanigans. Unaware Lena had a cold, the Wolf gets sick after kissing her so many times.
Lena Hyena has been confused with Lena the Hyena, a character from the comic strip Li'l Abner by Al Capp as they both have near-identical names and are comically hideous. There's been a long-standing rumor that Lena was loosely adapted from or was, at least, referencing the Li'l Abner character.
Lena's scene was heavily inspired by a segment from the 1943 Tex Avery short Red Hot Riding Hood where Grandma chases the Wolf after he mistakes her for Red. It also references the moment when he runs through a door and almost falls off a very tall apartment building.
The scene contains references to Disney's Alice in Wonderland; the doorknobs on Lena's floor appear highly similar to the Doorknob from the film and the graffiti on the bathroom wall reads "For a good time, call ALLYSON "WONDERLAND", the best is yet to be".
Lena in her brief Jessica guise
Lena in Roger Rabbit's Toontown: "The Kissing Bandit"