Eddie pursues Jessica into Toontown believing her to have just committed a murder. Upon arrival, he notices a half-silhouette of a woman resembling Jessica doing her hair in a hotel window and proceeds to intercept. Once he gets there, the seemingly stunning woman immediately reveals herself to be an ugly hag named Lena Hyena, who instantly falls in love and chases after him upon sight. Not knowing where to turn, he retreats into the men's restroom.
Eddie discovers the restroom is non-existent leading to open air a million miles high in the sky causing him to plummet countless stories. Just as he's about to hit the street below, Lena manages to catch him just in time and gives him a big kiss very much to his dismay. It's poweful recoil sends him flying several yards down the street. Still madly passionate for him, she continues to run after him. He quickly tears a street line and places it towards a brick wall to which she mindlessly follows, flattening upon impact.
Roger Rabbit's Toontown
Lena appears in the Roger Rabbit's Toontown issue, "The Kissing Bandit" where it's revealed she's actually been a long-time friend of Jessica. In the issue, Jessica visits Lena in Toontown as she's pursued by a Toon Wolf who's overly smitten by her. The Wolf keeps confusing Lena for Jessica in his multiple attempts to kiss her, much to his horror. He runs away not knowing what to learn from his shenanigans. Unaware Lena had a cold, the Wolf gets sick after kissing her so many times.
"Lena the Hyena"
There's been a long-standing rumor that Lena may have been loosely adapted from or was, perhaps, an obscure reference to Lena the Hyena, a character from the comic strip Li'l Abner by Al Capp. A resident of Lower Slobbovia, Lena the Hyena was said to be ugly to a point where it caused insanity. Her face was always hidden either by being censored or seen only from the neck down. In 1946, a nationwide drawing contest was held to find the best interpretation of her; the winner being future-Mad Magazineillustrator Basil Wolverton. While it remains unconfirmed, it seems most likely the two women are completely separate characters who just happen to have near identical names.
Lena's scene was heavily inspired by a segment from the 1943 Tex Avery short Red Hot Riding Hood where Grandma chases the Wolf after he mistakes her for Red. It also references the moment when he runs through a door and almost falls off a very tall apartment building.
Real saliva was used when she kissed Eddie.
The doorknobs on Lena's floor, seen on both the doors to her room and the incomplete bathroom, appear highly similar to the Doorknob from Alice in Wonderland.
Lena in her brief Jessica guise
Lena in Roger Rabbit's Toontown: "The Kissing Bandit"