After the Mighty Med hospital is destroyed by a band of unknown super-villains. Kaz, Oliver and Skylar join forces with Chase and Bree to form a powerful elite force that combines bionic abilities and superpowers. Together, they vow to track down the villains and keep the world safe.
- Billy Unger as Chase Davenport
- Bradley Steven Perry as Kaz
- Jake Short as Oliver
- Kelli Berglund as Bree Davenport
- Paris Berelc as Skylar Storm