He is well-known for portraying Childs in the 1982 sci-fi horror film The Thing. He also voiced the Cat in the 2009 stop-motion film Coraline, and played the CIA Director in the Agent Cody Banks films and Barricade in the Transformers film series.
For Disney, has voiced several Disney characters, most notably Goliath in Gargoyles, Tublat in The Legend of Tarzan, and Dr. Facilier in The Princess and the Frog. He also voiced Mr. Pig in the Timon & Pumbaa episode "Animal Barn", and the Cheshire Cat in Once Upon a Time in Wonderland. Additionally, he appeared in other ABC Studios TV shows.