Sir Isaac Newton (December 25, 1642 – March 20, 1726) was an English physicist and mathematician who was known as one of the most influential scientists of all time. In 1687, he published a book called Philosophiæ Naturalis Principia Mathematica and made contributions to optics.

Newton appeared as a chalkboard drawing in the Timon & Pumbaa episode "Hakuna Matata U." He was mentioned in the Spider-Man episode Take Two.