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I40
Lightning McQueen: "Whoa, look at that. Look, they're driving right by. They don't even know what they're missing!"
Sally: "Well, it didn't used to be that way."
McQueen: "Oh, yeah?"
Sally: "Yeah. Forty years ago, that Interstate down there didn't exist."
McQueen: "Really?"
Sally: "Yeah. Back then, cars came across the country a whole different way."
McQueen: "How do you mean?"
Sally: "Well, the road didn't cut through land like that Interstate. It moved with the land, you know? It rose, it fell, it curved."
Lightning McQueen and Sally, talking about I-40

Interstate 40 is a United States interstate running from Barstow, California, to North Carolina. Interstate 40 appears in Cars. Lightning McQueen and Mack start their drive to Los Angeles from the Motor Speedway of the South, and are seen afterwards driving west on the Interstate during the "Life is a Highway" sequence. The interstate is responsible for bypassing Radiator Springs (to save 10 minutes of driving, according to Sally) causing Radiator Springs to lose all its visitors and customers. The Top Down Truckstop is located along Interstate 40.

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Cars-Logo
Media
Cars/SoundtrackCars 2/SoundtrackCars 3/Original Motion Picture Soundtrack/Original Score SoundtrackMater and the GhostlightCars ToonsDisney's Wonderful World of ReadingLittle Golden BookVideo

Video Games: Cars: The Video GameCars 2: The Video GameCars: Mater-National ChampionshipCars: Race-O-RamaThe World of Cars OnlineCars: Radiator Springs AdventuresKinect Rush: A Disney/Pixar AdventureDisney INFINITYCars: Fast as LightningCars 3: Driven to Win

Disney Parks
Cars LandDisney's Art of Animation ResortArt of AnimationCars Quatre Roues RallyeDisney Animation BuildingLuigi's Flying TiresLuigi's Rollickin' RoadstersMater's Junkyard JamboreeRadiator Springs Racers

Entertainment: Moteurs... Action! Stunt Show Spectacular
Restaurants: Cozy Cone MotelFillmore's Taste-InFlo's V8 Cafe
Shops: Radiator Springs CuriosRamone's House of Body ArtSarge's Surplus Hut
Parade: Mickey's New Year's Eve ParadePaint The Night ParadePixar Play Parade
Firework: World of Color: Celebrate!

Characters
Cars: Lightning McQueenMaterSally CarreraMackThe KingChick HicksNot ChuckMia and TiaHarvBoostDJWingoSnot RodBob CutlassDarrell CartripDoc HudsonFloRamoneSheriffLuigiGuidoSargeFillmoreRedLizzieStanleyBessieJuniorTex DinocoLynda WeathersVanMinnyMichael Schumacher FerrariJay LimoFredToddFrankTractorsMikeSulleyVroomaroundus BugusRalph Carlow

Cars 2: Finn McMissileHolley ShiftwellCrabbyTony TrihullLeland TurboRod "Torque" RedlineMiles AxlerodMel DoradoProfessor ZündappGremAcerFrancesco BernoulliLewis HamiltonJeff GorvetteMax SchnellMiguel CaminoRaoul ÇaRouleNigel GearsleyCarla VelosoBrent MustangburgerDavid HobbscapVladimir TrunkovVictor HugoTubbs PacerJ. Curby GremlinFred PacerIvanAlexander HugoUncle TopolinoMama TopolinoOtisSiddeleyCartney Brakin
Cars 3: Cruz RamirezJackson StormNatalie CertainSterlingMiss FritterChase RacelottDanny SwervezRyan "Inside" LaneyBubba Wheelhouse<Cam Spinner<Rich MixonCal WeathersBobby SwiftTerry KargasHamiltonSmokey
Mater and the Ghostlight: Screamin' Banshee
Cars Toons: KabutoBig DSandy DunesBlue GritIdle ThreatShifty SidewinderDidi 05Mike 07
Video Games: CandiceEl MachismoStinger

Episodes
Mater's Tall Tales: Rescue Squad MaterMater the GreaterEl MaterdorTokyo MaterUnidentified Flying MaterMonster Truck MaterHeavy Metal MaterMoon MaterMater Private EyeAir MaterTime Travel Mater

Tales From Radiator Springs: HiccupsBuggedSpinningThe Radiator Springs 500½
Cancelled Episodes: To Protect and Serve

Songs
Real GoneLife is a HighwayOur TownSh-BoomRoute 66Find YourselfBehind the CloudsMy Heart Would KnowYou Might ThinkCollision of WorldsNobody's FoolRide
Organizations/Groups
DinocoThe Delinquent Road HazardsWorld Grand PrixLemons
Locations
Radiator SpringsCity HallMunicipal ImpoundTow Mater Towing & SalvageFlo's V8 CafeLuigi's Casa Della TiresRamone's House of Body ArtCozy Cone MotelFillmore's Taste-InSarge's Surplus HutSarge's SUV Boot CampDoctor Hudson: Dr. of Internal CombustionRacing MuseumMrs. PistonWilly's ButteRadiator Springs CuriosRadiator Springs Drive-In TheatreWheel Well MotelLondon, EnglandParis, FrancePorto CorsaTokyoCaliforniaU.S. Route 66Interstate 40Los Angeles International SpeedwayMotor Speedway of the SouthOrnament ValleyCadillac RangeCarburetor CountyBig BenTop Down TruckstopBig BentleyNASCAHollywoodThomasville
Objects
Piston CupAllinolBombEMP EmitterTripleDent Gum
See Also
The Science Behind PixarPixar in a Box