Originally a Maya warrior in ancient times, he was captured by the alien Kree, and became one of their first subjects to undergo Terrigenesis, a process used to create super soldiers known as Inhumans. Terrigenesis transforms him into a mass of cellular parasites which survives by inhabiting a dead human host, gaining their memories in the process, and he can manifest an alien-like head with protruding tentacles. Hive can expel the parasites to devour humans for nourishment, or infect Inhumans to "sway" them under his control in a hive mind. The ancient Inhumans feared him and used Kree technology to banish him to a faraway planet called Maveth. His remaining worshippers established a secret society to prepare the world for his return (ultimately evolving into the terrorist organization HYDRA) and provide new victims/hosts, including Lord Manzini (portrayed by Daniel J. Wolfe), Nathaniel Malick (portrayed by Joel Courtney), and NASA astronaut Will Daniels (portrayed by Dillon Casey). Through Hydra's efforts, Hive returns to Earth in the corpse of HYDRA leader Grant Ward (portrayed by Brett Dalton). Hive seizes control of HYDRA and recreates the Terrigenesis experiment, seizing a warhead to spread worldwide a virus that transforms humans into Hive-infected primitive Inhuman warriors. His efforts are thwarted by S.H.I.E.L.D. when Lincoln Campbell entraps them both in a space bound Quinjet containing the exploding warhead, killing them both.