Savino joined DTVA in 2010, where he served as executive producer of Kick Buttowski: Suburban Daredevil; he also directed or co-directed every episode. After Kick Buttowski ended, he directed and storyboarded the Mickey Mouse short Bad Ear Day. He left the studio in 2013.
He got his start in animation as a layout artist on The Ren & Stimpy Show, and is best known for his work on Cartoon Network series like Dexter's Laboratory and The Powerpuff Girls (1998). He is also the creator of the Nickelodeon animated series The Loud House.