Originally a group of students, the group was formed for the purpose of capturing the supervillain Yokai, the man responsible for the death of their friend (and Hiro's brother) Tadashi, and bringing him to justice. Thanks to the students' high intellect, the group built specialized suits based on the individual skills of each member, transforming themselves into high-tech superheroes. After not only stopping Yokai but also saving the city in effect, the team is coined "Big Hero 6" by the media and vow to protect San Fransokyo in honor of Tadashi.
“Do you feel it? You guys, do you feel this? Our origin story begins! We're gonna be superheroes!”
In the film, Fred gave the name Fred's angels to the team with his own theme song, a nod to Charlie's Angels.
In the original comics, the team was comprised of Baymax, Hiro Takachiho (Hiro's Marvel counterpart), Honey Lemon, Go Go Tomago, and Marvel mutants Silver Samurai and Sunfire. After the latter two left the team, Wasabi and Fred replaced them as the team's current roster. Due to Silver Samurai and Sunfire being owned by 20th Century Fox, Wasabi and Fred are introduced as the founding members of the team instead.