After their wedding Rachel and Sam decide to start their own life. The Langham Hotel is willing to let anybody who can take the place of the landscaper and chef live in the hotel. Sam and Rachel bring Chloe and Papi to the hotel where Chloe and Papi meet Oscar and Jenny, the hotel's Doggy Day School teachers. Papi is less than thrilled when he discovers he wills no longer be teaching the pups. Mr Hollis, the manager notices Chloe and asks if she can make apperances as the hotel has gained a major threat, Montague, the new hotel to rival the Langham. Because of this Sam and Rachel get the jobs. Rosa is also not much happier at the thought of Doggy Day School.
Pedro also comes along to the Langham decked out in sunnies. The humans, chihuahuas and Pedro are blown away at their room's luxury. However Rosa isn't feeling happy and is nervous about day school. Papi comforts her, telling her about how he was a chamberlain at a friend's Quincenera when Pedro finds a picture in box marked DO NOT OPEN. Papi tells her what a Quince is about. Later, Chloe, Sam and Rachel start work and the puppies go to school.
Rachel meets her boss, Chef Didei a bossy and tight man who is very fond of himself and very strict. When somebody quits Chef Didei says that he fired him. When he and Rachel meet he tells her to wash dishes and then throws herbs at her face when she asks if there was some confusion. Sam meets his assistant Lester who his lazy and tired who provides no reason for not helping and leaves Sam to do all the work. Rosa is being bullied by a large dog who teases her for having to wear swimmies. Rosa runs off upset and embarrassed and the puppies get payback on the dog. Papi finds Sam and offers assistance but just as he begins to help he hears a rustling sound and finds an overgrown messy garden with a gate. There he meets Arnie a resident stray dog who's a mute. Oscar then arrives as Jenny quickly leves not wanting to be seen or heard. Papi is concerned for the pups safety and asks Oscar what is going on. Oscar however, doesn't want to mention anything and leaves Papi to ponder what is going on. Arnie makes a carving of Jenny to warn Papi but Papi doesn't understand it.
Back at home, Rosa fakes sick to avoid going to school but when Papi says she'll have to go to the vet she claims she is feeling better. She claims she doesn't want to be little anymore and states she wants to be a Quince. When the other pups assume it is "One of dad's weird Mexican holidays," they state they want a sweet sixteen but Rosa says she wants a Quince and Papi promises to throw her one.
- Marcus Coloma as Sam Cortez
- Erin Cahill as Rachel Ashe Cortez
- Cedric Yarbrough as Hollis
- Frances Fisher as Amelia James
- Briana Lane as Jenny
- Sebastian Roche as Chef Frank Didier
- Jason Brooks as Mr. Montague
- Kyle Gass as Lester
- Amanda Fuller as Spa Employee
- Michael Lanahan as BellHop #1
- Sam Pancake as Frederick
- Eddie "Piolín" Sotelo as Hotel Security Guard
- Jeff Witzke as Cook
- Caren Boyajian as BellHop #2
- J.P. Manoux as Gustavo
- Cara Santana as Jillian
- Yuri Everson as Puppeteer #1
- David Penikas as Puppeteer #2
- George Lopez as Papi
- Odette Annable as Chloe
- Ernie Hudson as Pedro
- Kay Panabaker as Rosa
- Logan Grove as Papi Jr.
- Emily Osment as Pep
- Madison Pettis as Lala
- Delaney Jones as Ali
- Tom Kenny as Sebastian
- Jake Busey as Oscar
- Lacey Chabert as Charlotte
- Miguel Ferrer as Delgado
- Phil LaMarr as Diego
- Eddie "Piolín" Sotelo as Humberto
- Nick Eversman as Phil
- Lev L. Spiro as Black Labbeth Guitarist
- Phil LaMarr as Black Labbeth Bassist
- Jon Curry as Gunther
- Shawn Kavanaugh as Fluffy