- Sabrina Carpenter as Jenny Parker
- Sofia Carson as Lola Perez
- Sofia Warren as Madison Lawrence
- Madison Horcher as AJ Anderson
- Rachel Ramos as Talia Anderson
- Jet Jurgensmeyer as Bobby Anderson
- Max Gecowets as Trey Anderson
- Mallory James Mahoney as Katy Cooper
- Nikki Hahn as Emily Cooper
- Kevin Quinn as Zac Chase
- Max Lloyd-Jones as Officer James
- Gillian Vigman as Helen Anderson
A remake was reportedly planned for release in 2012. Raven-Symoné was going to star in it but decided to withdraw due to other projects. Miley Cyrus was also rumored to be attached to the project, but later denied involvement. Tiffany Paulsen was writing the script. It was presumed that it was scrapped due to years of inactivity. However, on January 9, 2015, Disney announced that it would go forward, with Sabrina Carpenter and Sofia Carson starring as competing babysitters.
- This film was celebrated as the 100th DCOM (Disney Channel Original Movie).
- The film was formerly called Further Adventures in Babysitting.