In the franchise, Adam is the youngest child and second son of Wayne and Diane Szalinski, born during the time skip between the first and second films. In Honey, I Blew Up the Kid, he is a typical 2-year-old toddler, despising naps and often getting into trouble due to his curiosity. Much of the film's struggle comes from the fact that he only registers his parents when they are bigger than he is. In Honey, We Shrunk Ourselves, he is at around ten. Unlike Nick, who shared his father's scientific interest, he prefers baseball to science, though he initially doesn't know how to explain this to his father.
When Diane takes Amy to college, Wayne is charged with watching Nick and Adam. On Saturday, he takes them to the lab where he works, in an attempt to get one last test run of his latest invention, a machine that enlarges matter. During the test, Adam unknowingly escapes from his stroller, and wanders into the machine's path. While nothing seems to happen at first, it is later seen that he grows when in close contact with the electromagnetic energy given off by electric-powered devices.
Though Wayne first attempts to return Adam to the lab to reverse the process, the presence of a coworker, Dr. Charles Hendrickson, who had been trying to take over Wayne's project, forces them to return home. By this time, Diane has returned, and is shocked to see that Adam is now over seven feet tall. While Wayne and Diane return to the lab to get Wayne's shrinking machine, Adam grows again to fourteen feet tall while watching TV and escapes through the house walls, forcing Nick and Mandy Park, his babysitter, to try to find him. All three are captured by Dr. Hendrickson, who reported them to the head of the labs, Clifford Sterling, and engaged law enforcement to track Adam down.
Adam grows again, this time due to being near electric wires, and escapes from the truck carrying him, picks up Nick and Mandy, puts them in his pocket, and takes them with him. He eventually ends up in Las Vegas, where he wanders around the Strip, thinking it's a playground. By this time, Wayne and Diane have come to town with the machine, assisted by Sterling, who has fired Dr. Hendrickson and offered the parents his support. Meanwhile, Adam, now over 100 feet tall, approaches a Hard Rock Cafe and rips off the guitar from its sign. An initial attempt to make Adam stay still by lulling him to sleep fails. After this, Dr. Hendrickson, angry at his firing, attempts to shoot Adam with tranquilizers. The first shot misses him, but the second hits the guitar, giving him a painful electrocuting shock, to which he starts crying. Luckily for him, Diane intervenes, temporarily enlarged due to the machine, and holds him, keeping him still long enough for Wayne to shrink them both, returning Adam to normal size.
Adam, now ten, has developed a love for baseball in contrast to his father's and brother's love of science and invention. However, Wayne desires to send him to science camp, and Adam had trouble making him understand his preferences.
When Diane and Aunt Patti prepare to go on a vacation, Adam is meant to stay at home with his father, Uncle Gordon, and cousins Jenny and Mitch. When the kids are sent to buy groceries, Wayne and Gordon accidentally shrink themselves while secretly trying to shrink a Tiki Man ornament Diane wants to throw out. When Diane and Patti return to drop off Mitch's medicine, they are also shrunk. When Adam, Jenny, and Mitch return home, they believe Diane and Patti to be on vacation. Meanwhile, an undeleted voicemail message leads them to believe that Wayne and Gordon have left unexpectedly to see a shuttle launch. While the adults try to get their kids' attention, they, thinking they have the house to themselves, invite friends over for a party.
During the adults' attempts, Wayne overhears Adam's desire to go to baseball camp rather than science camp, and comes to understand his interests better. Later on, Mitch becomes ill because of a potassium deficiency (he was unable to find the medicine his mother left for him). Adam is able to save him when he remembers Wayne telling him that bananas had potassium. When the adults finally get their kids' attention, Adam, Jenny and Mitch are able to get the machine ready thanks to Wayne's instructions. They briefly contemplate leaving their parents shrunk after Adam mentions the idea, but soon decide against it. After being returned to normal size, Wayne and Diane apologize to Adam for not listening to him when he said he didn't want to go to Camp Isosceles, as well as not realizing that he had different interests; Wayne then offers to send Adam to baseball camp.