- Buena Vista Games has been renamed to Disney Interactive Studios.
- Disney officially enters the Blu-ray market.
- After 27 years, the last Disney film to be released on VHS was Cars.
- Disney acquires Club Penguin.
- May - Touchstone Television has been renamed to ABC Studios which left Monk (USA Networks) is still use Touchstone Television logo until final season
- June 29 - After 12 years, the last Disney/Pixar film to use the Pixar-exclusive Walt Disney Pictures logo was Ratatouille.
- July 8 - Due to disappointing ticket sales, the Broadway production of Tarzan closed.
- July 29 - After a 13-year run, the Broadway production of Beauty and the Beast played its final performance.
- Disney dropped its brand name Buena Vista.
- January 12 - Primeval (Hollywood Pictures)
- February 16 - Bridge to Terabithia
- March 2 - Wild Hogs (Touchstone Pictures)
- March 30 - The 47th Disney animated feature film, Meet the Robinsons, was released to mixed to positive reviews.
- April 27 - The Invisible (The Last Movie was release by Hollywood Pictures.)
- May 25 - Pirates of the Caribbean: At World's End
- June 29 - Ratatouille, the last Disney/Pixar animated feature film to use the Pixar-exclusive Walt Disney Pictures logo and was released to universal acclaim.
- August 2 - Underdog was released to negative reviews.
- September 28 - The Game Plan is released to negative reviews.
- October 26 - Dan in Real Life (Touchstone Pictures)
- November 21 - Enchanted was released to universal acclaim.
- December 21 - National Treasure: Book of Secrets.
- June 29 - Lifted (Pixar short)
- November 6 - Your Friend the Rat
- December 21 - How to Hook Up Your Home Theater
- February 10 - Kim Possible season 4 premiered on the Disney Channel.
- February 12 - Jojo's Circus gets cancelled.
- February 26 - Power Ranger Operation Overdrive premiered on Toon Disney through Jetix.
- April 9 - The Doodlebops Season 3 permiered on Playhouse Disney.
- May 12 - My Friends Tigger & Pooh premiered on the Disney Channel's Playhouse Disney block.
- August 17 - The premiere of High School Musical 2 on the Disney Channel draws a cable television record 17.2 million viewers and easily beats the top ranked show on over-the-air television, America's Got Talent on NBC. The Disney Channel Original Series Phineas and Ferb also debuts with its pilot broadcast; it would officially premiere on February 1, 2008.
- September 7 - Kim Possible aired its final episode on the Disney Channel.
- November 10 - That's So Raven airs its series finale and 100th episode on the Disney Channel.
- November 12 - Power Ranger Operation Overdrive airs its final episode on Toon Disney through Jetix.
VHS, DVD & Blu-ray releases
- January 3 - The Little Mermaid: Platinum Edition (Disney Movie Club Exclusive VHS)
- January 16 - Read It and Weep: Zapped Edition and That's So Suite Life of Hannah Montana: Mixed-Up Mashed-Up Edition
- February 6 - Pirates of the Caribbean: Dead Man's Chest (Disney Movie Club Exclusive VHS)
- February 19 - Cars (Disney Movie Club Exclusive VHS) Last Pixar film released on VHS, and last Disney film overall released on VHS
- February 27 - Little Einsteins: Legend of The Golden Pyramid
- March 6 - Peter Pan: Platinum Edition
- April 3 - Jump In!: Freestyle Edition
- May 15 - Home Improvement: The Complete Sixth Season (Touchstone Television)
- May 22 - Scrubs: The Complete Fifth Season (Touchstone Television)
- June 12 - Primeval (Hollywood Pictures)
- June 19 - Bridge to Terabithia and The Many Adventures of Winnie the Pooh: The Friendship Edition
- June 26 - High School Musical: The Concert and Hannah Montana: Pop Star Profile
- July 31 - Roving Mars
- August 7 - The Suite Life of Zack & Cody: Sweet Suite Victory, Cory in the House: All-Star Edition, The Muppet Show: Season 2, Darkwing Duck: Volume 2, Home Improvement: The Complete Seventh Season (Touchstone Television), and 8 Simple Rules: The Complete First Season (Touchstone Television)
- August 14 - Wild Hogs (Touchstone Pictures)
- August 21 - Little Einsteins: Rocket's Firebird Rescue and Handy Manny: Tooling Around
- August 28 - Mickey Mouse Clubhouse: Mickey's Treat and Return to Halloweentown: Ultimate Secret Edition
- September 4 - Disney Princess Enchanted Tales: Follow Your Dreams and Desperate Housewives: The Complete Third Season (Touchstone Television)
- September 11 - Grey's Anatomy: The Complete Third Season (Touchstone Television)
- September 18 - Brothers & Sisters: The Complete First Season (Touchstone Television)
- September 25 - What About Brian: The Complete Series (Touchstone Television)
- October 2 - The Jungle Book: 40th Anniversary Platinum Edition
- October 9 - Hannah Montana: Life's What You Make It and Johnny Kapahala: Back on Board
- October 16 - The Invisible (Hollywood Pictures)
- October 23 - Meet the Robinsons
- October 30 - October Road: The Complete First Season (Touchstone Television) and Scrubs: The Complete Sixth Season (Touchstone Television)
- November 6 - Ratatouille and Pixar Short Films Collection, Vol. 1
- November 13 - DuckTales: Volume 3 and TaleSpin: Volume 2
- November 20 - The Santa Clause 3: The Escape Clause and My Friends Tigger & Pooh: Super Sleuth Christmas Movie
- November 27 - Wish Gone Amiss and Return to Never Land: Pixie-Powered Edition
- December 4 - Pirates of the Caribbean: At World's End
- December 11 - High School Musical 2: Extended Edition, Walt Disney Treasures: Disneyland - Secrets, Stories & Magic, Walt Disney Treasures: The Chronological Donald, Volume 3, Walt Disney Treasures: The Adventures of Oswald The Lucky Rabbit and Lost: The Complete Third Season (ABC Studios)
- December 18 - Underdog and National Treasure: 2-Disc Collector's Edition
- February 6 - Cinderella III: A Twist in Time
- December 18 - Cinderella II: Dreams Come True: Special Edition
Theme park happenings
- January 1- The Wonders of Life Pavillion closes at Epcot.
- January 4 - The Seas with Nemo & Friends at Epcot is officially dedicated.
- April 2 - The Monsters, Inc. Laugh Floor opens at the Magic Kingdom.
- April 6 - Gran Fiesta Tour Starring The Three Caballeros opens at Epcot.
- June 9 - Toon Studio opens at Walt Disney Studios Park.
- June 11 - Finding Nemo Submarine Voyage opens at Disneyland.
- June 26 - At Walt Disney Studios Park, a 14-year-old girl loses consciousness on Rock 'n' Roller Coaster. Paramedics attempted to revive her, but she died before the ambulance arrived.
- August 9 - It is announced that the Disney-MGM Studios at Walt Disney World will be rebranded as "Disney Hollywood Studios", effective January 1, 2008.
- September 13 - The Haunted Mansion at Magic Kingdom reopens with some new scenes and other enhancements.
- September 24 - The Main Street Haunted Hotel opens at Hong Kong Disneyland for the Halloween season.
- October 17 - Cars Land is first announced.
- December 22 - The Twilight Zone Tower of Terror opens at Walt Disney Studios Park.
- March 29 - Kingdom Hearts Re:Chain of Memories (Japan, included for Kingdom Hearts II Final Mix+)
- June 26 - Ratatouille: The Video Game is released in North America.
- August 9 - Ratatouille: The Video Game is released in Australia.
- September 28 - Ratatouille: The Video Game is released in Europe.
- October 23 - Ratatouille: The Video Game is released in North America on the PlayStation 3.
- October 26 - High School Musical: Sing It! is released in North America as an interactive singing karaoke game.
- October 29 - Cars: Mater-National Championship is released in North America.
- November 15 - High School Musical: Sing It! is released in Europe and Australia.
- November 29 - Cars: Mater-National Championship is released in Australia.
- November 30 - Cars: Mater-National Championship is released in Europe.
- October - Disney Adventures publishes its final issue
- May 1 - Percy Jackson and The Olympians: The Titan's Curse
- June 6 - Aubrey Anderson-Emmons (child actress)
- July 27 - Alyvia Alyn Lind (child actress)
- August 28 - August Maturo (child actor)
- January 8 - Iwao Takamoto (animator)
- February 9 - Ian Richardson (Scottish actor)
- February 12 - Peter Ellenshaw (artist)
- February 15 - Walker Edmiston (voice actor)
- April 11 - Roscoe Lee Browne (actor and director)
- April 14 - Jim Thurman (voice actor)
- April 30 - Tom Poston (actor)
- May 7 - Fulton Burley (Irish-born Disney Legend)
- May 17 - Lloyd Alexander (author)
- May 22 - Art Stevens (animator)
- May 25 - Charles Nelson Reilly (actor, comedian and director)
- June 4 - Ray Erlenborn (film, television and voice cctor)
- July 2 - Beverly Sills (operatic soprano)
- July 9 - Charles Lane (character actor)
- July 13 - Lawrence Gabriel, Jr. (actor, drama teacher and occasional producer)
- July 15 - Kieron Moore (film and television actor)
- September 6 - Luciano Pavarotti (operatic tenor)
- September 8 - Charlie Parlato (musician)
- September 10 - Jane Wyman (singer, dancer and character actress)
- October 2 - Kōichi Kitamura (Japanese voice actor)
- October 17 - Teresa Brewer (pop singer)
- October 30 - Robert Goulet (baritone singer)
- November 6 - Bruce Gordon (Imagineer)
- December 17 - Jack Zander (animator)
- August 17 - Phineas Flynn, Ferb Fletcher, Perry the Platypus, Candace Flynn, Linda Flynn, Major Monogram, Dr. Doofenshmirtz, Isabella Garcia-Shapiro, Ginger Hirano, Katie
- September 4 - Duke (Sleeping Beauty)
- September 28 - Jeremy Johnson, Stacy Hirano, Buford Van Stomm, Jenny Brown, Django Brown, Adyson Sweetwater, Gretchen, Holly, Milly
- November 21 - Giselle