- May 10 - The Broadway production of Tarzan officially opens.
- July 7 - Walt Disney Pictures introduced its current logo in front of Pirates of the Caribbean: Dead Man's Chest.
- October 6 - The Disney Movie Rewards program begins.
- November 16- Following the success of the West End production, a Broadway production of Mary Poppins officially opens.
- December 12 - After 21 years, the last Disney movie to use the original Walt Disney Pictures logo was The Fox and the Hound 2.
- January 13 - Glory Road
- January 27 - Roving Mars
- February 17 - Eight Below
- March 10 - The Shaggy Dog, the remake starring Tim Allen, opens to theaters. Reviews were very mixed, and was at a time on the Bottom 100 movies list on the Internet Movie Database and it maintains a 4.2/10 rating as of February 11, 2012.
- April 14 - The Wild
- June 9 - Cars
- July 7 - Pirates of the Caribbean: Dead Man's Chest
- August 25 - Invincible
- October 27 - The Nightmare Before Christmas (reissue)
- November 3 - The Santa Clause 3: The Escape Clause
- December 8 - Apocalypto under Touchstone Pictures.
- June 9 - One Man Band
- January 20 - High School Musical premieres on Disney Channel and draws an astonishing 7.8 million viewers for its' premiere.
- January 27 - The Emperor's New School premieres on Disney Channel.
- March 24 - Hannah Montana premieres on Disney Channel.
- May 5 - Mickey Mouse Clubhouse premieres on Disney Channel.
- May 22- Alias ends its run on ABC.
- July 28 - The Replacements premieres on Disney Channel.
- September 2 - ABC Sports becomes "ESPN on ABC", utilizing ESPN graphics.
- June 21 - The first issue of the new Gargoyles comic book by Slave Labor Graphics is published.
- November - Gemstone stops publishing Mickey Mouse and Friends and Donald Duck and Friends.
- March 28 - Kingdom Hearts II for PlayStation 2
- June 5 - Cars
- October 19 - Kim Possible: What's the Switch? for PlayStation 2
- March 21 - Percy Jackson and the Olympians: The Sea of Monsters
- October 3 - Disney Dossiers: Files of Characters From the Walt Disney Studios
Theme park happenings
- January 23 - Monsters, Inc. Mike & Sulley to the Rescue! opens at Disney's California Adventure, replacing Superstar Limo.
- April 5 - Cinderella Castle Mystery Tour closes at Tokyo Disneyland.
- April 7 - Expedition Everest opens at Disney's Animal Kingdom.
- April 8 - Buzz Lightyear Laser Blast opens at Disneyland Paris.
- July 13 - Autopia, UFO Zone and Stitch Encounter open at Hong Kong Disneyland.
- July 25 - Matt Ouimet steps down as president of the Disneyland Resort to become president of the Hotel Group of Starwood Hotels & Resorts Worldwide. Ed Grier, former executive managing director of Walt Disney Attractions Japan, takes over as president of the Disneyland Resort.
- July 31 - Disney announces the demise of the "Sword in the Stone" show at Magic Kingdom as part of the "Year of a Million Dreams" promotion (it will be replaced by another show called the Royal Court Academy).
- August 19 - Who Wants to Be a Millionaire – Play It! closes at Disney-MGM Studios, almost two years to the day that its California Adventure counterpart closed.
- September 22 - Tower of Terror opens at Tokyo DisneySea.
- September 30 - Disneyland's 50th anniversary celebration ends. Club Buzz at Disneyland reopens as Tomorrowland Terrace.
- October 2 - The Year of a Million Dreams promotion begins.
- January 24 - The Walt Disney Company announced that it will acquire Pixar Animation Studios. As part of the merger, Steve Jobs (the owner of Pixar) becomes the chief shareholder in the company. Shortly thereafter, the Feature Animation department is reopened (having been shut down two years earlier), and John Lasseter is put in charge of Imagineering in the theme parks.
- February 9 - The Walt Disney Company regains rights to Oswald the Lucky Rabbit from NBC Universal, as part of a deal which sent sportscaster Al Michaels from Disney’s ABC and ESPN to NBC Sports.
- February 28 - Lady and the Tramp: 50th Anniversary Platinum Edition
- March 7 - Chicken Little
- April 4 - The Chronicles of Narnia: The Lion, the Witch and the Wardrobe
- April 11 - The Greatest Game Ever Played and Pooh's Grand Adventure: The Search for Christopher Robin (Special Edition)
- May 23 - High School Musical: Encore Edition
- June 6 - Glory Road and Dumbo: Big Top Edition
- June 20 - Lady and the Tramp II: Scamp's Adventure: Special Edition
- August 1 - The Shaggy Dog
- August 29 - Darkwing Duck: Volume 1, TaleSpin: Volume 1
- September 5 - Happy Haunting: Party at Disneyland
- October 3 - The Little Mermaid: Platinum Edition
- October 10 - The Fox and the Hound: 25th Anniversary Edition
- October 24 - Wendy Wu: Homecoming Warrior
- October 31 - The Wild
- November 7 - Cars
- November 14 - Adventures of the Gummi Bears: Volume 1, DuckTales: Volume 2 and Chip 'n Dale Rescue Rangers: Volume 2
- November 28 - Robin Hood: Most Wanted Edition and The Cheetah Girls 2
- December 5 - Pirates of the Caribbean: Dead Man's Chest
- December 19 - Invincible, Walt Disney Treasures: Your Host Walt Disney, Walt Disney Treasures: The Complete Pluto, Volume 2, Walt Disney Treasures: More Silly Symphonies, Walt Disney Treasures: The Hardy Boys - The Mickey Mouse Club
- February 7 - Bambi II
- August 29 - Brother Bear 2
- December 12 - The Fox and the Hound 2 and Air Buddies
- January 6 - Lou Rawls (soul, jazz and blues singer)
- February 24 - Don Knotts and Dennis Weaver (voice actor and actor)
- February 25 - Darren McGavin (actor)
- March 8 - Rhoda Williams (voice actress)
- March 22 - Britt Lomond (actor and producer)
- June 28 - Lennie Weinrib (actor, voice actor and writer)
- July 13 - Red Buttons (actor)
- July 19 - Jack Warden (character actor)
- July 20 - Gérard Oury (film director, actor and writer)
- July 21 - Mako Iwamatsu (actor)
- August 11 - Mike Douglas (singer)
- August 13 - Tony Jay (voice actor)
- August 28 - Ed Benedict (animator and layout artist)
- September 7 - Bernard Wolf (animator and television producer)
- September 23 - Tim Rooney (mouseketeer and child of Mickey Rooney)
- September 12 - Anita Gordon (voice actress)
- October 20 - Jane Wyatt (actress)
- December 8 - Martha Tilton (singer)
- December 12 - Peter Boyle (actor)
- December 18 - Joseph Barbera (animator, director, producer, storyboard artist, and cartoon artist)
- January 27 - Malina, Guaca
- June 9 - Lightning McQueen, Mater, Chick Hicks, Doc Hudson, Luigi, Guido
- July 28 - Todd and Riley Daring, Dick Daring, Agent K, C.A.R.